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Cosmelan Depigmentation

The gold standard for stubborn pigmentation

At a Glance

Pain Level

Warmth and slight stinging

Downtime

5-7 days of peeling

Sessions

Single in-clinic session + home programme

Duration

In-clinic application takes 30 minutes

Results

Significant within 2-4 weeks

Frequency

Once, with maintenance programme

What is Cosmelan Depigmentation?

Cosmelan is the world's leading professional depigmentation treatment, effective against all types of dark spots including melasma, sun damage, and post-inflammatory hyperpigmentation. This intensive programme delivers dramatic results for even the most stubborn pigmentation.

How It Works

The Cosmelan masque is applied in-clinic and left on for a prescribed period. It contains a potent blend of depigmenting agents that inhibit melanin production at a cellular level. You continue treatment at home with the Cosmelan 2 cream to maintain and enhance results.

Benefits

  • Most effective pigmentation treatment available
  • Tackles melasma and deep pigmentation
  • Long-lasting results with maintenance
  • Suitable for all skin types
  • Clinically proven worldwide

Is This Right for You?

Those with stubborn pigmentation, melasma, or dark spots that have not responded to other treatments.

You may benefit if you have:

  • Melasma (including stubborn, recurring patches)
  • Post-inflammatory hyperpigmentation from acne or trauma
  • Sun damage and age spots
  • Uneven skin tone across the face
  • Pigmentation that has not responded to other treatments

What to Expect During Your Visit

  1. 1

    Skin analysis

    Your therapist reviews your skin history, the depth and type of pigmentation, and explains the full protocol including home care.

  2. 2

    In-clinic masque application

    The Cosmelan masque is applied evenly across the face and left on for a prescribed period based on your skin.

  3. 3

    Masque removal at home

    You remove the masque at the specified time and begin your at-home protocol straight away.

  4. 4

    Guided home protocol

    You use Cosmelan 2 cream as part of a daily regimen. We support you with check-ins throughout.

  5. 5

    Follow-up review

    We review progress at key intervals, adjusting your routine to maintain and enhance results.

Premium Products We Use

Cosmelan by Mesoestetic

Pre-Treatment Care

  • Avoid sun exposure, tanning beds, and self-tanner for at least 2 weeks before treatment
  • Discontinue retinoids, AHAs/BHAs, and active skincare for 5-7 days prior
  • Do not undergo laser, waxing, or aggressive treatments on the same area
  • Skin should be calm, no active irritation, inflammation, or infection
  • Arrive with clean, makeup-free skin
  • Inform your practitioner about any medications or skin conditions
  • Maintain good hydration for optimal skin response

Post-Treatment Care

  • Follow the prescribed Cosmelan home-care protocol strictly as instructed
  • Redness, tightness, and peeling are expected and part of the treatment process
  • Do not pick, peel, or scrub the skin
  • Avoid sun exposure completely and apply SPF 50+ strictly and repeatedly
  • Avoid heat (sauna, steam, hot showers) and exercise for 48 hours
  • Avoid makeup for the first 24-48 hours or as advised
  • Discontinue all active skincare unless prescribed
  • Maintain hydration and a gentle skincare routine
  • Strict sun protection and compliance are essential to prevent rebound pigmentation and ensure optimal results

Who This Treatment Is Not Suitable For

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This treatment may not be right for you if any of the following apply. Please discuss your full medical history with us during consultation.

  • Active skin infection or open wounds in the treatment area
  • Known allergy to any Cosmelan ingredients
  • Pregnancy and breastfeeding
  • Very sensitive or compromised skin barrier
  • Recent aggressive treatments such as laser or deep peels (requires healing time)

Frequently Asked Questions

Why is Cosmelan so effective for melasma?

Cosmelan works by inhibiting the enzyme tyrosinase, which is responsible for melanin production. Unlike treatments that only address existing pigment, Cosmelan prevents new melanin from forming, which is why it is so effective for recurring conditions like melasma.

Ready to Book?

Start with a personalised consultation. Our experts will assess your skin and recommend the best approach for you.

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+971 4 330 6464Mon - Sat: 10 AM - 7 PM

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